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Онкология

Making invisible cancers visible: A new route to turn 'cold' tumors 'hot'

One of the biggest challenges in cancer immunotherapy may not be that immune cells are too weak, but that some tumors give them too little to see. New research from Dana-Farber Cancer Institute scientists reveals how cancers carrying mutations in the p53 tumor-suppressor protein can hide those mutations from T cells…

Онкология

Cancer biologists bring in the B-cell reinforcements for immunotherapy

Cancer is the second-leading cause of death in the United States, according to a 2026 Cancer Research Institute report. Cancer biologists are keenly aware of this statistic, as it drives innovations that revolutionize cancer care—innovations like immunotherapy. Immunotherapy fights cancer using the body's own immune…

Онкология

Early changes in the tumor environment may explain why immunotherapy works for some patients but not others

Two patients receive the same immunotherapy for the same cancer. In one, the tumor retreats and stays gone for years. In the other, the treatment does nothing. Oncologists still have no reliable way to tell these patients apart before therapy begins. Why does immunotherapy succeed for some and fail for others?