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Онкология

Scientists identify the neuroblastoma cells that signal poor outcomes

Neuroblastoma is the most common solid tumor found outside the brain in children, yet why some children respond well to treatment while others do not has remained poorly understood. St. Jude Children's Research Hospital scientists and their collaborators built one of the most comprehensive datasets of neuroblastoma…

Онкология

Abdominal fluid reveals rare immune cells that may limit attacks on tumors

In a study published in Science Immunology, researchers used malignant ascites—fluid that accumulates in the abdomen of some patients when cancer metastasizes to the abdominal cavity—to uncover immune programs associated with metastatic disease, including a rare population of RORC-expressing dendritic cells not…