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Онкология

Real-world data indicate lower adherence rates for breast cancer endocrine therapy when radiation therapy is omitted

Many patients with early-stage breast cancer do not consistently maintain the long-term hormone therapy prescribed after lumpectomy, a large U.S. insurance claims analysis indicates. The findings provide real-world context for treatment approaches that consider omitting radiation therapy, which typically rely on the…

Онкология

Landmark trial evaluates chemotherapy benefit in high-risk early-stage breast cancer

The addition of CDK4/6 inhibitors to endocrine therapy has changed the standard of care for patients with high-risk, early-stage estrogen receptor-positive, HER2-negative (ER+/HER2-) breast cancer by reducing the risk of recurrence. However, one patient subgroup continues to present a clinical dilemma. In current…