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BioNTech halts mRNA colorectal cancer vaccine trial after safety review - Reuters

BioNTech halts mRNA colorectal cancer vaccine trial after safety review Reuters

A liver signaling pathway may explain why colorectal cancer weakens muscle and bone

Researchers at the University of Colorado Anschutz and Indiana University School of Medicine have identified a biological process that may help explain why colorectal cancer can cause severe muscle and bone loss, especially in its most advanced stages. The condition, known as cancer cachexia, can leave patients weak…

<![CDATA[Botensilimab/Balstilimab Elicits Major Pathologic Responses in Colon Cancer]]>

Genetic ancestry has significant link to colorectal cancer risk

Genetic ancestry may have significant associations with colorectal cancer incidence and age-specific risk. An evaluation of more than 300,000 individuals with whole genome sequencing showed that individuals with European ancestry had greater overall odds of developing colorectal cancer, but other lineages, including…

Mucus-coated tumor spheres reveal potential targets to curb colorectal cancer spread

Researchers from the University of Turku in Finland and Gustave Roussy Institute in France have discovered a molecular mechanism that regulates whether cells in an aggressive colorectal cancer are conventional or inverted as they spread in the body. The discovery can help identify patients at elevated risk of the…

Colorectal cancer screening program helps save lives in Spain

Colorectal cancer mortality fell 50% over 21 years among individuals aged 50 to 69 years in a rural region in Spain, coinciding with the implementation of a population-wide fecal immunochemical test-based screening program. A retrospective analysis of more than 2 million individuals living in the Basque Country of…

This yeast supplement may boost cancer-fighting immunity

A simple yeast-based food supplement may help restore the immune system’s ability to fight cancer, according to new research in mice. Scientists found that yeast beta-glucan reprogrammed early immune cells in the bone marrow, leading to stronger, longer-lasting cancer-fighting responses against colorectal, skin, and…