Blocking the glycine transporter SLC6A20 restored important brain signaling and improved social, communication, and repetitive behaviors in autism-related mouse models. The treatment also worked in human brain organoids and showed lasting effects in adult mice, suggesting the brain may remain more treatable later in…
Chemotherapy-surviving ovarian cancer cells may release fructose to help neighboring tumor cells loosen, escape, and spread. The discovery suggests that sugary diets and cholesterol-lowering drugs could influence cancer progression, though the effects have not yet been confirmed in patients.
Cancer cells rely on powerful genetic switches to keep growth genes running at full speed, but that intense activity can damage their own DNA. The resulting breaks are repeatedly repaired, sometimes with small mistakes that allow new mutations to accumulate. Researchers believe this self-inflicted damage may help…
Scientists have identified an immune response that may explain why statins cause muscle pain, weakness, and exercise intolerance in some people. The finding could eventually lead to treatments that protect muscles while preserving the drugs’ lifesaving cardiovascular benefits.
Blood cancers that eventually worsen may carry detectable genetic warning signs years before patients develop serious symptoms. The findings could lead to earlier intervention while also helping doctors distinguish true cancer from harmless age-related blood changes.
The American Cancer Society study provides key financial data that helps underscore the value of cancer prevention and early detection
A controlled mouse study has provided direct evidence that inherited genetics can steer how cancer begins and evolves after DNA damage. The discovery could eventually help doctors better predict cancer risk and tailor screening and treatments to each patient.
Scientists used CRISPR to make prostate cancer cells easier for the immune system to detect and destroy. The experimental treatment dramatically improved the effects of immunotherapy in mice and may offer hope for other hard-to-treat tumors.
American Cancer Society researchers suggest integrating palliative care earlier and more consistently into routine oncology care is needed
Scientists uncovered how influenza A commandeers human cells, including a surprising strategy that dissolves tiny structures in the nucleus and releases proteins the virus may use to reproduce. The detailed molecular map could reveal new drug targets and help researchers study dangerous flu strains such as H5N1.
A naturally occurring compound found in foods such as wheat germ, mushrooms, and aged cheese may help older adults build stronger protection after vaccination. In a small pilot trial, researchers gave spermidine supplements to adults over 65 following their third COVID-19 vaccine dose. The biggest improvements…
Нейробластома — это злокачественное новообразование, которое развивается из клеток-предшественников нервной системы — нейробластов. Данная опухоль преимущественно встречается у детей. До 90% всех случаев нейробластомы выявляются в возрасте до 5 лет. Однако нельзя исключить вероятность ее развития и у взрослых. По…
Ингибиторы PARP — современная группа таргетных противоопухолевых препаратов, которые блокируют ферменты поли(АДФ-рибоза)-полимеразы (poly(ADP-ribose) polymerase, сокращенно PARP). Эти ферменты участвуют в репарации поврежденной ДНК. Под действием ингибиторов PARP этот процесс нарушается, в генах возникают... The post…