Colorectal cancer mortality fell 50% over 21 years among individuals aged 50 to 69 years in a rural region in Spain, coinciding with the implementation of a population-wide fecal immunochemical test-based screening program. A retrospective analysis of more than 2 million individuals living in the Basque Country of…
Older adults with mild cognitive impairment and sleep problems who took at least 5,000 IU of vitamin D daily scored more than 13% higher on a cognitive test than those taking none. The preliminary findings suggest vitamin D could be worth studying as a potentially modifiable factor during an early window of cognitive…
A simple yeast-based food supplement may help restore the immune system’s ability to fight cancer, according to new research in mice. Scientists found that yeast beta-glucan reprogrammed early immune cells in the bone marrow, leading to stronger, longer-lasting cancer-fighting responses against colorectal, skin, and…
The FDA is seeking feedback on a potential way of regulating medical devices equipped with generative AI features, informed by the process of training human clinicians. Described as a “competency-based approach,” the process would evaluate AI-equipped devices in increasingly clinical scenarios, including potentially…
Of more than 1,300 AI medical devices cleared by the FDA, only three tested for patient-centered outcomes like death and morbidity, data show. AI integration into healthcare is rapidly progressing. Medical societies like the AMA have called for stricter regulations due to concerns about bias and transparency in…
AI may be able to predict how strongly someone will respond to a vaccine before they receive it. By analyzing antibody patterns in more than 4,000 people, researchers found signs of “immune readiness” that helped distinguish strong responders from weak ones. Surprisingly, even some healthy people responded poorly…
ACOG strengthened its recommendation that OB/GYNs perform salpingectomy during hysterectomy and other surgeries to lower the risk for ovarian cancer. The latest guidance highlights evidence supporting the removal of both fallopian tubes “as a safe and effective method of reducing patients’ lifetime risk of ovarian…
An updated clinical guideline is designed to clarify the settings in which radiation therapy is appropriate for pancreatic cancer and outline how the modality can be integrated safely with other treatments. The guideline — which updates recommendations that American Society for Radiation Oncology (ASTRO) issued in…
Heidi Overton, MD, PhD, has been nominated to lead the FDA. The pick from President Donald J. Trump comes months after Martin Makary, MD, resigned from the position in May. Trump made the announcement in a Truth Social post Wednesday, calling Overton “a ROCKSTAR” in the administration, “where she has worked directly…
CMS has updated its guidance on prior authorization metrics reporting, addressing the AMA’s concerns about how health insurers were disclosing requirements and outcomes, according to the organization. The AMA said it notified CMS about issues with reporting metrics after it conducted a review examining how 15 Medicare…
A phase 3 trial found that a combination of intismeran autogene plus pembrolizumab improved recurrence-free and distant metastasis-free survival in patients with high-risk melanoma, according to topline data from the manufacturer. The randomized, double-blind INTerpath-001 trial evaluated intismeran autogene…
Collaborative investment will improve access to cancer care by providing no-cost lodging and support for patients and families
Engineered probiotic bacteria were able to infiltrate pancreatic tumors, stimulate cancer-fighting immune cells, and slow tumor growth in animal studies. Even more strikingly, the treatment worked better when combined with chemotherapy, radiation, or immunotherapy.
Postmenopausal women with breast cancer who reside in more socioeconomic deprived areas may not derive as much cognitive benefit from aerobic exercise as those who reside in more advantaged areas, noted Myeong-ga Cho, PhD, RN. In a Healio video exclusive, Cho detailed how aerobic exercise, neighborhood deprivation and…
Breast cancer is rising rapidly among Asian American women, with some of the most alarming increases occurring in younger women and in aggressive or advanced cancers. Researchers say screening alone can't explain the surge, suggesting important risk factors may still be undiscovered.