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Онкология

Novel CAR-T therapy shows promising safety and durable responses in hard-to-treat multiple myeloma

A phase 1 clinical trial led by investigators at Mass General Brigham Cancer Institute and the University of Chicago Medicine Comprehensive Cancer Center has found that an investigational CAR-T therapy can lead to deep and durable responses in people with relapsed or refractory multiple myeloma. Results are published…

Онкология

One gene helps drive growth in two childhood brain tumor groups that lack targeted therapies

Targeting KDM2B or downstream protein complexes it recruits may exploit a vulnerability in high-risk medulloblastoma subgroups that currently lack targeted therapies, according to a study led by St. Jude Children's Research Hospital and Hopp Children's Cancer Center Heidelberg (KiTZ). The researchers found that Group…

Онкология

Earlier stem cell transplants may improve survival in rare inherited bone marrow disorder

More than 90% of children born with the rare bone marrow condition Shwachman-Diamond syndrome (SDS) survive beyond age 20. But fewer than 30% live beyond age 50. Long-term survival could improve if clinicians act on early signs of high risk, according to a study published, in The New England Journal of Medicine.