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Онкология

Metabolic activity of gut bacteria can either promote or inhibit function of CAR T cells in cancer therapy

Immunotherapies, especially CAR T-cell therapy, have fundamentally changed cancer treatment in recent years, particularly for certain forms of leukemia and lymphoma. Yet not all tumors respond equally well, and the reasons for this remain incompletely understood. A new multicenter study by the Leibniz Institute for…

Онкология

Stomach bacterium hijacks healing signals to drive precancerous changes, study finds

Stomach cancer is one of the deadliest forms of cancer. Unlike many other types of cancer, however, one of its main causes is well known: chronic infection with the bacterium Helicobacter pylori. A team headed by Charité—Universitätsmedizin Berlin has revealed for the first time how such an infection reprograms the…